Phytochemical and elemental composition of the Linaria cretacea Fisch ex Spreng (Plantaginaceae)


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Authors

  • M.S. Bakytzhanova Abai Kazakh National Pedagogical University
  • K.H. Makhmudova Abai Kazakh National Pedagogical University
  • A.U. Tuyakbayeva L.N. Gumilyov Eurasian National University
  • N.A. Utarbayeva K. Zhubanov Aktobe Regional University
  • A.A. Bitkeyeva Toraighyrov University
  • T. Atici Gazi University

DOI:

https://doi.org/10.32523/2616-7034-2025-151-2-169-183

Keywords:

Linaria cretacea Fisch. ex Spreng., endemic, structural components, calcefite compound, phytochemical analysis

Abstract

The article presents the results of a phytochemical study of a rare species of the Republic of Kazakhstan Linaria cretacea Fisch ex Spreng. Specific biologically active compounds contained in the inflorescences, roots, and leaves of plants have demonstrated their pharmacological properties and biological activity, confirming that various phytochemical groups and individual compounds have beneficial effects. Of the total number of organic compounds detected in ethanol extracts, falcarinol (with a relative content of 16,51%) and thymol (with a relative content of 0,57%) in L. cretacea were identified with a high degree of confidence (65-90%). These compounds are valuable biologically active substances used in medicine. Being unsaturated compounds, they can be classified as natural antioxidants. For example, falcarinol is found in the roots of American ginseng. Thymol, which is part of the structural elements of cell membranes, is also a phenolic antiseptic with pronounced antimicrobial and antifungal activity against various microorganisms. The results obtained are promising and can be further used to develop a technology for obtaining valuable biologically active substances from Linaria cretacea Fisch ex Spreng biomass.

Published

2025-06-30

How to Cite

Bakytzhanova, M., Makhmudova, K. ., Tuyakbayeva, A., Utarbayeva, N. ., Bitkeyeva, A. ., & Atici, T. . (2025). Phytochemical and elemental composition of the Linaria cretacea Fisch ex Spreng (Plantaginaceae). BULLETIN of the L.N. Gumilyov Eurasian National University. BIOSCIENCE Series, 151(2), 169–183. https://doi.org/10.32523/2616-7034-2025-151-2-169-183

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