The research of the antibacterial activity of yeast Saccharomyces cerevisiae var. boulardii Az-12


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Authors

  • A.A. Saparbekova M.Auezov South-Kazakhstan State University
  • A.S. Latif M.Auezov South-Kazakhstan State University
  • Z.R. Ahmedova Institute of Microbiology, Academy of Sciences of the Republic of Uzbekistan

Keywords:

yeast, Saccharomyces cerevisiae, probiotics, antogenism, conditionally pathogenic and pathogenic bacteria

Abstract

The problem of treatment and prevention of acute intestinal infections is urgent in all countries without
exception. The strain Saccharomyces cerevisiae Az-12, isolated from the juice of pomegranate, grown in the Turkestan region,
shows the features of the probiotic culture Saccharomyces cerevisiae var. boulardii. Saccharomyces cerevisiae Az-12 antago
nistic abilities were studied with the following conditionally pathogenic or pathogenic bacteria: Escherichia coli, Enterococcus
faecalis, Pseudomonas aeruginosa, Salmonella typhimurium, Staphylococcus aureus as the most common bacteria associated
with diarrhea diseases. Saccharomyces cerevisiae Az-12 has a distinct inhibitory relationship to Staphylococcus aureus and
Escherichia coli. It has been proven that probiotic activity of Saccharomyces cerevisiae Az-12 against human pathogens is
due to a decrease in bacterial growth and due to the adherence of bacteria to the walls of yeast cells. Probiotic yeast cultures
Saccharomyces cerevisiae var. boulardii Az-12 can be used as a preventive and therapeutic agent for the treatment of various
diarrheal diseases.

Published

2026-06-07

How to Cite

Saparbekova, A., Latif, A., & Ahmedova З. (2026). The research of the antibacterial activity of yeast Saccharomyces cerevisiae var. boulardii Az-12. BULLETIN of the L.N. Gumilyov Eurasian National University. BIOSCIENCE Series, 128(3), 80–89. Retrieved from https://bulbio.enu.kz/index.php/main/article/view/989

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